STUDYING THE CHRONIC TOXICITY OF SULFOPARIN
Keywords:
Drug Sulfoparin, chitosan, chronic toxicity, cumulative properties.Abstract
For the first time, a set of preclinical experimental studies of the new drug “Sulfoparin”, developed by the Institute of Chemistry and Physics of Polymers of the Academy of Sciences of the Republic of Uzbekistan, was carried out. It has been established that with chronic exposure for 3 months, the drug in doses of 500, 100 and 25 mg/kg b.w. does not cause pathological changes in the body of experimental animals. Morphological studies have established that no significant differences were found in the structure of internal organs between the experimental and control groups, meaning Sulfoparin does not cause dystrophic, necrobiotic and inflammatory changes in animals.
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