THE ROLE OF COMORBIDITY IN THE CLINICAL MANIFESTATIONS OF GASTRODUODENAL ULCER IN THE POPULATION OF LONG-LIVED PEOPLE
Keywords:
comorbid, screening, factor, risk.Abstract
The authors of this article conducted a screening study based on WHO recommendations (2018) on a representative unorganized population on the role of comorbidity in the clinical picture of gastroduodenal ulcers in a population of centenarians. In the study, the simultaneous addition of another disease to a gastroduodenal ulcer (GDU) creates a new clinical situation. This situation requires doctors to select specific pharmacotherapy and prevention. Therefore, comorbid diseases are characterized as a poorly studied area of modern science, especially preventive medicine.
References
Atherton J.C. The clinical relevance of strain types of Helicobacter pylori. Gut. 1997; 40(6):701-703. DOI: 10.1136/gut.40.6.701
Charpignon C., Lesgourgues B., Pariente A., Nahon S., Pelaquier A., Gatineau Sailliant G., et al. Peptic ulcer disease: one in five is related to neither Helicobacter pylori nor aspirin/NSAID intake. Aliment Pharmacol Ther. 2013; 38(8):946-954. DOI: 10.1111/apt. 12465
Atherton J.C., Cao P., Peek R.M. Jr, Tummuru M.K., Blaser M.J., Cover T.L. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem. 1995; 270(30): 17771-17777. DOI: 10.1074/jbc. 270.30.17771
Goenka M.K., Majumder Majumder S., Sethy P.K., Chakraborty M. Helicobacter pylori negative, non-steroidal anti-inflammatory drug-negative peptic ulcers in India. Indian J Gastroenterol. 2011; 30(1):33-37. DOI: 10.1007/s12664-011-0085-9.