POLYCYSTIC OVARY SYNDROME: MODERN INSIGHTS INTO PATHOGENESIS AND CLINICAL MANAGEMENT
Abstract
Polycystic Ovary Syndrome (PCOS) is a complex chronic endocrine disorder characterized by ovulatory dysfunction, hyperandrogenism, and polycystic ovarian morphology. It affects approximately 5–20% of women of reproductive age worldwide, making it one of the most common causes of infertility and metabolic disturbances in women. PCOS is associated not only with reproductive dysfunction but also with metabolic, cardiovascular, and psychological complications. This paper discusses the latest insights into the pathogenesis, classification, clinical manifestations, and management of PCOS, emphasizing the multifactorial nature of the syndrome and its long-term health implications.
References
Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Human Reproduction, 2003.
Teede HJ et al. “Recommendations from the 2023 International Evidence-Based Guideline for the Assessment and Management of PCOS.” Fertility and Sterility, 2023.
Lizneva D et al. “Criteria, Prevalence, and Phenotypes of PCOS.” Fertility and Sterility, 2016.
Azziz R. “PCOS: An Endocrine Society Clinical Practice Guideline.” Journal of Clinical Endocrinology & Metabolism, 2018.
Goodarzi MO, Dumesic DA. “Pathogenesis of Polycystic Ovary Syndrome.” Nature Reviews Endocrinology, 2021.
Sirmans SM, Pate KA. “Epidemiology, Diagnosis, and Management of PCOS.” Clinical Epidemiology, 2014.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
