THE IMMUNE STATUS AND SPECIFICITY OF LIPID PEROXIDATION PROCESSES IN PATIENTS WITH HYPERTENSION

Authors

  • D.T.Sodiqova Faculty of medical advancement department of professional and re-training of family physicians, folk medicine and functional diagnostics Andijan State Medical Institute,Andijan, Uzbekistan

Keywords:

cardiovascular diseases, lipid peroxidation, immune status, low-dialdehyde.

Abstract

According to modern concepts, lipid peroxidation (LPO) is a constantly occurring physiological process that, when intensified, is involved in the development of a number of pathologies. It has been established that activation of LPO processes is involved in the pathogenesis of many diseases of the cardiovascular system [2]. Lipid peroxides play an important role in the body: lipoperoxides are an important intermediate in the biosynthesis of prostaglandins E, progesterone; they are involved in the hydroxylation of the cholesterol core; they are necessary for activating a number of membrane processes and regulating membrane permeability.

References

Belenkov Yu.N., Ageev F.T., Mareev V.Yu. Neurohormones and cytokines in heart failure: a new theory of an old disease? Heart failure. 2009, No. 1, pp. 13-17.

Gitel E.P., Gusev D.E., Ponomar E.G. The role of interleukins in the pathogenesis of atherosclerosis. //Clinical medicine. 2006, No. 6, pp. 10-15.

Kotovskaya M.A., Solovyov S.K., Nikishina N.Yu. Risk factors for atherosclerosis and clinical signs of cardiovascular disorders in patients at an early stage. // Rheumatology. 2005, No. 3, pp. 67-70.

Nasonov E.L. Immunological markers of atherosclerosis // Ter.archive, 2012; No. 5, pp. 80-85.

Paleev N.R., Paleev F.N. Cytokines and their role in the pathogenesis of heart diseases. Clinical medicine. 2004, No. 5, pp. 4-7.

Paleev N.R. Lipids and their role in the pathogenesis of heart diseases. // Clinical medicine. – Moscow, 2004. -No. 5.- From 4-7.

Makolkin V.I., Podzolkov V.I. Hypertension. // Appendix to the journal "Doctor" M.: Publishing house "Russian doctor", 2010, 96 p.

Libby P. Modern ideas about the pathogenesis of acute coronary syndromes. // Blood circulation. – 2011. -No. 104. – p. 365-372.

Uzui H., Harpf A., Liu M. et al. Increased expression of type 3 membrane metalloproteinase in human atherosclerotic plaque: the role of activated macrophages and inflammatory cytokines //Blood circulation. - 2012. - No.106. – p.3024–3030.

Davidenkova E.F., Lieberman I.S. Stroev Yu.I. et al. Indicators of lipid metabolism and lipid peroxidation system in men, taking into account the hereditary predisposition to atherosclerotic vascular pathology. //Cardiology. – Moscow, 1991.-№8. - 41-44.

Urumbaev R.K., Titeev G.R., Boyarkina O.V. and others. Characteristics of lipid peroxidation in healthy individuals and patients with atherosclerosis. //Center.- Asian medical journal. Bishkek, 2003. -No. 1. -pp. 16.

Ogilvy R.L., Burgess E.D., Gisson J.R. Report of the Consensus Conference of the Canadian Society for Hypertension. 3: V Pharmacological treatment of essential hypertension. Can McdAsso.cj. 2013; 149:575-584.

Published

2024-11-17

How to Cite

D.T.Sodiqova. (2024). THE IMMUNE STATUS AND SPECIFICITY OF LIPID PEROXIDATION PROCESSES IN PATIENTS WITH HYPERTENSION. Ethiopian International Journal of Multidisciplinary Research, 11(11), 334–336. Retrieved from https://www.eijmr.org/index.php/eijmr/article/view/2139