KREBS CYCLE MANAGEMENT, STAGES AND DYSFUNCTION

Authors

  • Qosimov A Andijan State Medical Institute, Uzbekistan

Keywords:

Krebs cycle, ATP, cellula , Hans, oxygen , glycolysis, NADH.

Abstract

Krebs cycle is a cyclical metabolic pathway that oxidizes acetyl CoA, a two-carbon molecule derived from various fuel sources such as glucose, fatty acids, and amino acids. It extracts high-energy electrons from the acetyl CoA molecules and transfers them to electron carriers, such as nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), which become reduced to NADH and FADH, respectively. These electron carriers then participate in the subsequent oxidative phosphorylation and electron transport chain reactions, leading to the production of ATP.

References

Alabduladhem, T. O., & Bordoni, B. (2022). Physiology, krebs cycle. In StatPearls [Internet]. StatPearls Publishing.

Budin, I., de Rond, T., Chen, Y., Chan, L. J. G., Petzold, C. J., & Keasling, J. D. (2018). Viscous control of cellular respiration by membrane lipid composition. Science, 362(6419), 1186-1189.

Gasmi, A., Peana, M., Arshad, M., Butnariu, M., Menzel, A., & Bjørklund, G. (2021). Krebs cycle: activators, inhibitors and their roles in the modulation of carcinogenesis. Archives of Toxicology, 95(4), 1161-1178.

Ryan, D. G., & O’Neill, L. A. (2020). Krebs cycle reborn in macrophage immunometabolism. Annual review of immunology, 38, 289-313.

Ryan, D. G., Murphy, M. P., Frezza, C., Prag, H. A., Chouchani, E. T., O’Neill, L. A., & Mills, E. L. (2019). Coupling Krebs cycle metabolites to signalling in immunity and cancer. Nature metabolism, 1(1), 16-33.

Stubbs, R. T., Yadav, M., Krishnamurthy, R., & Springsteen, G. (2020). A plausible metal-free ancestral analogue of the Krebs cycle composed entirely of α-ketoacids. Nature chemistry, 12(11), 1016-1022.

Дусмухамедов, Д. М., Юлдашев, А. А., & Хакимова, З. К. (2020). ОБЩИЙ СТОМАТОЛОГИЧЕСКИЙ СТАТУС У БОЛЬНЫХ ГНАТИЧЕСКИМИ ФОРМАМИ АНОМАЛИИ ОККЛЮЗИИ. ББК 1 P76, 30.

Dusmukhamedov, D. M., Dusmukhamedov, M. Z., & Khakimova, Z. K. (2019). ESTIMATION OF MORPHOMETRIC CHANGES OF UPPER RESPIRATORY WAYS IN PATIENTS WITH DENTAL JAW DEFORMITIES. In Colloquium-journal (No. 28-3, pp. 5-6). Голопристанський міськрайонний центр зайнятості= Голопристанский районный центр занятости.

Дусмухамедов, М. З., Юлдашев, А. А., Дусмухамедов, Д. М., & Хакимова, З. К. (2022). ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ БОЛЬНЫХ С ВТОРИЧНЫМИ ДЕФОРМАЦИЯМИ ВЕРХНЕЙ ГУБЫ ПОСЛЕ ОДНОСТОРОННЕЙ ХЕЙЛОПЛАСТИКИ. ЖУРНАЛ СТОМАТОЛОГИИ И КРАНИОФАЦИАЛЬНЫХ ИССЛЕДОВАНИЙ, 3(3).

Salomov, S. N. O. G. L., Aliyev, H. M., & Dalimova, M. M. (2022). RECONSTRUCTIVE RHINOPLASTY METHOD WITH EXTERNAL NOSE DEFORMATION AFTER UNILATERAL PRIMARY CHEILOPLASTY. Central Asian Research Journal for Interdisciplinary Studies (CARJIS), 2(10), 87-90.

Shoxabbos, S., & Mahramovich, K. S. M. K. S. (2023). CAUSES OF THE ORIGIN OF CARDIOVASCULAR DISEASES AND THEIR PROTECTION. IQRO JURNALI, 1-6.

Maxmudovich, A. X., Raximberdiyevich, R. R., & Nozimjon o’g’li, S. S. (2021). Oshqozon Ichak Traktidagi Immunitet Tizimi. TA'LIM VA RIVOJLANISH TAHLILI ONLAYN ILMIY JURNALI, 1(5), 83-92.

Published

2023-10-08

How to Cite

Qosimov A. (2023). KREBS CYCLE MANAGEMENT, STAGES AND DYSFUNCTION. Ethiopian International Journal of Multidisciplinary Research, 10(09), 387–395. Retrieved from https://www.eijmr.org/index.php/eijmr/article/view/261