PERFORATED ULCER OF THE STOMACH AND DUODENUM: CLINICAL, DIAGNOSTIC, AND SURGICAL ASPECTS

Jaloliddinov Sh.I.

Authors

Jaloliddinov Sh.I. Ferghana Medical Public Health Institute

Keywords:

gastrointestinal perforation, peptic ulcer pathology, acute peritoneal inflammation, presence of free intraperitoneal air, diagnostic evaluation, operative management.

Abstract

A perforation of the gastric or duodenal wall constitutes a life-threatening surgical emergency marked by the disruption of the organ’s structural integrity and the subsequent translocation of luminal contents into the peritoneal cavity. This pathological event significantly heightens the risk of diffuse peritonitis, systemic sepsis, and multiorgan dysfunction, thereby necessitating prompt and decisive medical intervention. This article explores the underlying pathophysiological mechanisms, clinical manifestations, diagnostic approaches, and therapeutic strategies associated with perforated peptic ulcers, in addition to examining the epidemiological trends of this condition.

References

Abdrashitov K. Z. Peptic Ulcer Disease of the Stomach and Duodenum. — 2017. — No. 4. — pp. 22–27.

Lazovsky Yu. M. Mechanism of Perforation in Peptic Ulcer Disease. — 2015. — Vol. 19, No. 1. — pp. 12–18.

Rybakov I. M. Surgical Treatment of Peptic Ulcer Disease. — 2000. — Vol. 30, No. 2. — pp. 42–47.

Isaqova, N. R. (2022). Influence of constipation on anthropometric indicators of children. Science and Innovation, 1(8), 888-892.

Raxmatjonovna, I. N. (2023). Effects of colonic diseases on children’s health. World bulletin of public health, 23, 101-103.

Jurabaev A.A., Eshbaev E.A., Mamasaidov Zh.T. - Pathomorphological changes in necrotic enterocolitis of the lateral layer of the intestinal//New Day in Medicine 11(73)2024 964-970

Мамасаидов Ж. Т., Джурабаев А. А., Эркин А. Э. Некротик энтероколитда ингичка ичак шиллиқ қаватининг патоморфологияси //Журнал гуманитарных и естественных наук. – 2024. – №. 17. – С. 200-205.

Kuzin M. I. Operations for Peptic Ulcer Disease: Modern Approaches. — 2005. — No. 8. — pp. 56–60.

Krasilnikov D. M. Early Postoperative Complications in Patients with Peptic Ulcer Disease. — 2019. — Vol. 22, No. 1. — pp. 29–35.

Jaloliddinov Sh.I. World of Science. — 2024. — pp. 38–41.