STUDYING OF PROTECTIVE FACTORS OF THE ORAL CAVITY
Keywords:
protective factor, antimicrobial peptide, barrier, histatine Hst-5Abstract
Antimicrobial peptides provide the first line of defense for oral tissues against the introduction of pathogens. Several groups of antimicrobial peptides have been found in the oral cavity, which have different origins and are active against bacteria, fungi and viruses, as well as having the properties of immunomodulators and chemoattractants. Antimicrobial peptides play a crucial role in maintaining oral health.
References
Paster BJ, Olsen I, Aas JA, Dewhirst FE. The breadth of bacterial diversity in the human periodontal pocket and other oral sites. Periodontology 2000. 2006;42(1):80-87. doi:10.1111/j.1600-0757.2006.00174.x.
Рабинович О.Ф., Рабинович И.М., Абрамова Е.С. Изменение микробной флоры при патологии слизистой оболочки рта. Стоматология. 2011;6:71-76.
Hans M, Madaan Hans V. Epithelial antimicrobial peptides: guardian of the oral cavity. International Journal of Peptides. 2014;2014:1-13. doi:10.1155/2014/370297.
Вавилова Т.П., Янушевич О.О., Островская О.Г. Слюна. Аналитические возможности и перспективы. М.: БИНОМ; 2014.
Gaspar D, Veiga AS, Castanho MA. From antimicrobial to anticancer peptides. A review. Frontiers in Microbiology. 2013;294(4):1-16. doi:10.3389/fmicb.2013.00294.
Reddy KV, Yedery RD, Aranha C. Antimicrobial peptides: premises and promises. International Journal of Antimicrobial Agents. 2004;24(6):536-547. doi:10.1016/j.ijantimicag.2004.09.005.
Dale BA, Fredericks LP. Antimicrobial Peptides in the Oral Environment: Expression and Function in Health and Disease. Curren Issues Molecular Biology. 2005;7(2):119-133. doi:10.1093/jac/dki103.
Будихина A.С., Пинегин Б.В. Дефензины — многофункциональные катионные пептиды человека. Иммунопатология, аллергология, инфектология. 2008;2:31-40.
Ganz T, Selsted ME, Szklarek D, Harwig SS, Daher K, Bainton DF, Lehrer I. Defensins. Natural peptide antibiotics of human neutrophils. Journal of Clinical Investigation. 1985;76(4):1427-1435. doi:org/10.1172/jci112120.
Ericksen B, Wu Z, Lu W, Lehrer RI. Antibacterial activity and specificity of the six human alfa-defensins. Antimicrobial Agents and Chemotherapy. 2005;49(1):269-275. doi:10.1128/AAC.49.1.269-275.2005.
Salomov, S. N. O. G. L., Aliyev, H. M., & Dalimova, M. M. (2022). RECONSTRUCTIVE RHINOPLASTY METHOD WITH EXTERNAL NOSE DEFORMATION AFTER UNILATERAL PRIMARY CHEILOPLASTY. Central Asian Research Journal for Interdisciplinary Studies (CARJIS), 2(10), 87-90.
Shoxabbos, S., & Mahramovich, K. S. M. K. S. (2023). CAUSES OF THE ORIGIN OF CARDIOVASCULAR DISEASES AND THEIR PROTECTION. IQRO JURNALI, 1-6.
Maxmudovich, A. X., Raximberdiyevich, R. R., & Nozimjon o’g’li, S. S. (2021). Oshqozon Ichak Traktidagi Immunitet Tizimi. TA'LIM VA RIVOJLANISH TAHLILI ONLAYN ILMIY JURNALI, 1(5), 83-92.
