PLASMAPHERESIS IN RHEUMATOID ARTHRITIS: CLINICAL OBSERVATIONS
Keywords:
rheumatoid arthritis, plasmapheresis, extracorporeal therapy, immune complexes, DAS28, autoimmunity.Abstract
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive joint damage and systemic complications. Despite the widespread use of conventional disease-modifying therapies and biological agents, some patients exhibit resistance or intolerance to medications. Extracorporeal methods, including therapeutic plasmapheresis, are gaining importance as an adjunctive measure to reduce autoimmune activity. The present study aims to evaluate the clinical effectiveness of plasmapheresis in patients with active RA.
References
Smolen J.S., Aletaha D., McInnes I.B. Rheumatoid arthritis. The Lancet. 2016;388(10055):2023–2038.
McInnes I.B., Schett G. The pathogenesis of rheumatoid arthritis. N Engl J Med. 2011;365(23):2205–2219.
Singh J.A., Saag K.G., Bridges S.L. et al. 2015 American College of Rheumatology guideline for the treatment of rheumatoid arthritis. Arthritis Care Res. 2016;68(1):1–25.
Kuroda T., Shimada K., Ueda H. et al. Use of plasma exchange in autoimmune disease. Ther Apher Dial. 2014;18(6):498–504.
Zhou J., Wang C., Yang Y. et al. Therapeutic plasma exchange in autoimmune diseases: an updated systematic review and meta-analysis. Autoimmun Rev. 2019;18(1):102–110.
Yoshida A., Takeuchi T., Tanaka Y. et al. Plasma exchange in treatment-resistant cases of rheumatoid arthritis. Mod Rheumatol. 2017;27(2):278–283.
Umemoto T., Fujita S., Sakai M. et al. Efficacy of therapeutic apheresis for autoimmune diseases. Clin Hemorheol Microcirc. 2020;75(3):367–375.
Wada H., Okamoto K., Konishi T. et al. Recent progress in the management of rheumatoid arthritis. Jpn Med Assoc J. 2012;55(2):124–130.
Пулатов С. С., Латипов Р. Ж. ЛЕЧЕБНО-МЕДИКАМЕНТОЗНАЯ БЛОКАДА ПРИ ОСТЕОХОНДРОЗЕ // Экономика и социум. 2024. №12-1 (127). URL: https://cyberleninka.ru/article/n/lechebno-medikamentoznaya-blokada-pri-osteohondroze (дата обращения: 19.04.2025).
Тян Д. Л., Валиев Р. А., Пулатов С. С. ПОДВОДНОЕ ВЫТЯЖЕНИЕПОЗВОНОЧНИКА ПРИ ОСТЕОХОНДРОЗЕ //Journal of Healthcare and Life-Science Research. – 2024. – Т. 3. – №. 9. – С. 160-162.
Pulatov S. S., Valiev R. A. RESPIRATORY PHYSIOTHERAPY INTERVENTIONS IN ACUTE VIRAL RESPIRATORY INFECTIONS: A COMPREHENSIVE THERAPEUTIC EXPLORATION //Экономика и социум. – 2023. – №. 12 (115)-1. – С. 581-582
Valiev R. A. Professional Athletes' Perspectives on the Function of Sports Medicine Specialists in Treating Psychosocial Aspects of Sport-Injury Rehabilitation //International Journal of Integrative and Modern Medicine. – 2024. – Т. 2. – №. 7. – С. 215-221.
Butabaev M. T., Valiyev R. A. NEUROREHABILITATION OF THE MUSCULOSKELETAL SYSTEM OF ATHLETES USING THE STRESS EFFECT OF NATURAL FACTORS //Ethiopian International Journal of Multidisciplinary Research. – 2023. – Т. 10. – №. 09. – С. 473-474.
Butabaev, M. T., & Pulatov, S. S. (2023). BIOPSYCHOSOCIAL FACTORS IN THE REHABILITATION OF ELDERLY PATIENTS WITH DISEASES OF THE NERVOUS SYSTEM. Ethiopian International Journal of Multidisciplinary Research, 10(09), 468-470.
