NEUROLOGICAL CHANGES AND DIAGNOSTIC EVALUATION ALGORITHM IN UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA
Keywords:
Undifferentiated connective tissue dysplasia, collagen and elastin disorders, neurological changes, autonomic dysfunction, genetic factors, diagnostics.Abstract
Undifferentiated connective tissue dysplasia (UCTD) is a heterogeneous group of disorders characterized by pathological changes in various organs and systems. Despite its widespread occurrence, the clinical manifestations - particularly neurological changes - remain insufficiently studied. This article analyzes the clinical features, pathogenetic mechanisms, and diagnostic approaches to neurological disorders in patients with UCTD.
References
Malfait F. et al. Am J Med Genet C, 2019; 181(1): 6–28.
Castori M. Curr Opin Neurol, 2020; 33(5): 652–660.
De Paepe A., Malfait F. Clin Genet, 2021; 99(2): 135–145.
Kadurina T.I., Gorbunova V.N. Phenotyping of Connective Tissue Disorders, 2009.
Hakim A. et al. Rheumatology, 2019; 58(4): 582–592.
Rombaut L. et al. J Vasc Res, 2020; 57(3): 145–156.
Beighton P. Pediatr Rheumatol Online J, 2019; 17: 32.
Colombi M. et al. Cephalalgia, 2021; 41(9): 1045–1055.
Abbakumova L.N. Vestnik Nevrologii, 2020; №4: 45–52.
Rowe P.C. Clin Auton Res, 2020; 30(5): 427–438.
Smith T. BMJ, 2022; 376: e0650.
Tinkle B. J Child Neurol, 2021; 36(2): 105–115.
Van Damme T. Clin Chim Acta, 2019; 495: 210–218.
Lapina N.V., Belova Ye.A. Rossiyskiy Meditsinskiy Zhurnal, 2022; №3: 30–35.
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