OTOMYCOSIS IN PATIENTS WITH DIABETES MELLITUS: CLINICAL COURSE AND CHARACTERISTICS OF OTOMYCOSIS IN PATIENTS WITH DIABETES MELLITUS
Keywords:
Otomycosis; Diabetes mellitus; Fungal ear infection; External auditory canal; Immunocompromised patientsAbstract
Otomycosis is a superficial fungal infection of the external auditory canal that is frequently encountered in otolaryngological practice, especially in tropical and subtropical regions. Patients with diabetes mellitus represent a particularly vulnerable group due to immune dysfunction, altered local microenvironment, and metabolic changes associated with chronic hyperglycemia. The presence of diabetes not only increases susceptibility to otomycosis but also influences its clinical course, severity, recurrence rate, and response to treatment. This article provides a comprehensive review of the clinical features, pathophysiology, diagnostic challenges, and management of otomycosis in patients with diabetes mellitus. Emphasis is placed on the role of impaired immunity, common fungal pathogens, and the importance of glycemic control in achieving favorable outcomes. Understanding the unique aspects of otomycosis in diabetic patients is essential for early diagnosis, effective treatment, and prevention of complications.
References
Jackman A, Ward R, April M, Bent J. Topical antibiotic induced otomycosis. Int J Pediatr Otorhinolaryngol. 2005;69(6):857–860.
Munguia R, Daniel SJ. Ototopical antifungals and otomycosis: a review. Int J Pediatr Otorhinolaryngol. 2008;72(4):453–459.
Prasad SC, Kotigadde S, Shekhar M, et al. Primary otomycosis in the Indian subcontinent: predisposing factors, microbiology, and classification. Int J Microbiol. 2014;2014:636493.
Stern JC, Lucente FE. Otomycosis. Ear Nose Throat J. 1988;67(11):804–810.
Rubin Grandis J, Branstetter BF, Yu VL. The changing face of malignant (necrotizing) external otitis: clinical, radiological, and anatomic correlations. Lancet Infect Dis. 2004;4(1):34–39.