URINARY STONE DISEASE: ETIOLOGY, CLINICAL MANIFESTATIONS, AND MANAGEMENT STRATEGIES

Dilmurodov Davlat O’tkirovich

Authors

Dilmurodov Davlat O’tkirovich Asia International University, Bukhara, Uzbekistan

Abstract

Urolithiasis, commonly known as urinary stone disease, refers to the formation of calculi (stones) within the urinary tract, including the kidneys, ureters, bladder, and urethra. It is a multifactorial disorder with increasing global prevalence, contributing significantly to patient morbidity and healthcare burden. This article discusses the pathophysiology, risk factors, clinical presentation, diagnostic modalities, and current management strategies for urinary stone disease.

References

Bhave, P. B., & Tandon, S. (2021). "Urinary Stones: Diagnosis and Management." International Journal of Urology, 28(6), 509-518. DOI: 10.1111/iju.14417.

Pak, C. Y., & Cupples, W. E. (2020). "Etiology and Pathogenesis of Urolithiasis." Urology, 135, 14-19. DOI: 10.1016/j.urology.2019.10.012.

Boyer, L. et al. (2019). "Epidemiology of Urinary Tract Stones: A Systematic Review." European Urology, 76(1), 21-25. DOI: 10.1016/j.eururo.2019.01.019.

Stoller, M. L., & Tefekli, A. (2018). "Management of Urinary Stones: An Overview." Nature Reviews Urology, 15(10), Varma & Dhananjay, 651-661. DOI: 10.1038/s41585-018-0076-0.

Mason, R. J. et al. (2017). "Clinical Manifestations of Urolithiasis." American Journal of Kidney Diseases, 70(5), 697-703. DOI: 10.1056/NEJMra1600752.

Mayo Clinic Staff. (2023). "Kidney stones: Symptoms and causes." Retrieved from Mayo Clinic.

Siekmann, M., & Ghani, K. R. (2020). "Advances in the Management of Urinary Stone Disease." British Journal of Urology International, 125(2), 194-204. DOI: 10.1111/bju.14916.

Narasimhan, A. et al. (2021). "Dietary Factors in the Prevention of Calcium Oxalate Stones: A Review." Urology, 150, 1-8. DOI: 10.1016/j.urology.2020.08.026.

Sorensen, M. D., & Hsu, D. (2018). "The Role of Medical Therapy in Urolithiasis." Urologic Clinics of North America, 45(4), 615-625. DOI: 10.1016/j.ucl.2018.06.013.

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). (2018). "Kidney Stones." Retrieved from NIDDK.