COMPARATIVE HISTOLOGICAL ANALYSIS OF LIVER TISSUE IN NON-ALCOHOLIC FATTY LIVER DISEASE

Kapizova Dilafruz Rakhmonjonovna

Authors

Kapizova Dilafruz Rakhmonjonovna Department of Medical Biology and Histology Andijan State Medical Institute Andijan, Uzbekistan

Keywords:

NAFLD, NASH, liver histology, steatosis, fibrosis, inflammation.

Abstract

Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders worldwide, closely associated with obesity, insulin resistance, and metabolic syndrome. Histological examination remains the gold standard for evaluating disease severity and progression. This article presents a comparative histological analysis of liver tissue in different stages of NAFLD, including simple steatosis and non-alcoholic steatohepatitis (NASH). Structural alterations such as lipid accumulation, hepatocellular ballooning, inflammatory infiltration, and fibrosis are analyzed. Understanding histological differences between disease stages is essential for accurate diagnosis and appropriate clinical management.

References

Esteva, A., Robicquet, A., Ramsundar, B., et al. (2019). A guide to deep learning in healthcare. Nature Medicine, 25(1), 24–29.

Kengesbayevich, R. M. (2025). PERSONAL VALUES IN THE STRUCTURE OF SPIRITUAL AND MORAL EDUCATION. AMERICAN JOURNAL OF MULTIDISCIPLINARY BULLETIN, 3(1), 1-4.

Topol, E. J. (2019). High-performance medicine: The convergence of human and artificial intelligence. Nature Medicine, 25(1), 44–56.

Salomov, S. N. O. G. L., Aliyev, H. M., & Dalimova, M. M. (2022). RECONSTRUCTIVE RHINOPLASTY METHOD WITH EXTERNAL NOSE DEFORMATION AFTER UNILATERAL PRIMARY CHEILOPLASTY. Central Asian Research Journal for Interdisciplinary Studies (CARJIS), 2(10), 87-90.

Chilamkurthy, S., et al. (2018). Deep learning algorithms for detection of critical findings in head CT scans. The Lancet, 392(10162), 2388–2396.

Titano, J. J., et al. (2018). Automated deep-neural-network surveillance of cranial images for acute neurologic events. Nature Medicine, 24(9), 1337–1341.

Kengesbayevich, R. M. (2025). Features of Fairy Tale Therapy and Puppet Therapy and Possibilities of Their Combination. Spanish Journal of Innovation and Integrity, 40, 182-183.

Kengesbayevich, R. M. (2025). DIDACTICS OF PHYSICAL CULTURE AND SPORT. In International Conference on Adaptive Learning Technologies (Vol. 13, pp. 20-21).

Salomov, S., Aliyev, X. M., Rakhmanov, P. P., Ashurova, M. D., & Makhamatov, U. S. (2022). HISTOSTRUCTURE OF THE GASTRIC MUCOUS MEMBRANE OF RATS WITH A SINGLE PROTEIN DIET. EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE, 2(4), 14-16.Kengesbayevich, R. M. (2025). The Relationship of Emotional Atmospheric Climate in Junior High School Classes at School. Spanish Journal of Innovation and Integrity, 40, 224-226.

Kengesbayevich, R. M. (2025). Causes of Emotional Burnout of Teachers. Spanish Journal of Innovation and Integrity, 40, 186-187.

Саломов, Ш. Н., & Мадумарова, М. М. (2022). ЎСМИРЛАРДА ФИБРОМИАЛГИЯНИ КЕЛТИРИБ ЧИҚАРУВЧИ ОМИЛЛАР. Central Asian Research Journal for Interdisciplinary Studies (CARJIS), 2(10), 83-86.

Kengesbayevich, R. M. (2025). Problems of Life Activity of the Elderly. Spanish Journal of Innovation and Integrity, 40, 180-181.

Kelly, C. J., Karthikesalingam, A., Suleyman, M., Corrado, G., & King, D. (2019). Key challenges for delivering clinical impact with artificial intelligence. BMC Medicine, 17, 195.