COMPARATIVE ASSESSMENT OF MORPHOLOGICAL MARKERS IN THE BRAIN IN EPILEPSY

Muxammadsodik Soliyevich Isroilov,Tursunaliyeva Moxigul Dilshodjon qizi

Authors

Muxammadsodik Soliyevich Isroilov,Tursunaliyeva Moxigul Dilshodjon qizi Central Asian Medical University

Keywords:

epilepsy, neuromorphology, morphological markers, hippocampal sclerosis, pyramidal neurons, reactive gliosis, synaptogenesis, cortical dysplasia, apoptosis, microcirculation.

Abstract

This comprehensive scientific article presents a comparative analysis of the fundamental morphological basis of epilepsy, the pathological transformation of neuronal structures, and the microscopic markers in brain tissue. The study provides an in-depth discussion of the interrelationship among hippocampal sclerosis, focal cortical dysplasia, gliosis, and synaptic reorganization, as well as the role of these changes in the development of drug resistance[1,2,3].

Statistical data from Uzbekistan and global medicine between 2024 and 2026, together with innovative neuromorphological advances and diagnostic criteria, are presented in an integrated academic text. The article analyzes strategies for improving surgical and therapeutic effectiveness through identification of the morphological substrate of epilepsy.

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