SPECIFIC FEATURES OF CHRONIC HEART FAILURE IN MIDDLE-AGED AND ELDERLY PATIENTS IN THE KHOREZM REGION

Sultonnazarova Gulira'no Shuxratbek qizi

Authors

Sultonnazarova Gulira'no Shuxratbek qizi 2nd year student of the master's degree in cardiology at the Urgench State Medical Institute

Keywords:

chronic heart failure, Khorezm, middle-aged, elderly, cardiovascular disease

Abstract

Chronic heart failure (CHF) remains a significant public health concern worldwide, particularly in low- and middle-income countries. In Uzbekistan, and specifically in the Khorezm region, the prevalence of CHF among middle-aged and elderly populations has been steadily rising. This study aims to investigate the clinical characteristics, progression, and outcomes of CHF in these age groups, focusing on regional specificities. Data were collected from clinical observations, patient records, and structured questionnaires. Findings suggest that elderly patients experience more severe manifestations of CHF, with higher hospitalization rates and comorbidities compared to middle-aged patients. Regional lifestyle factors, limited access to advanced medical care, and delayed diagnosis contribute to the worsening disease profile. The study highlights the urgent need for improved diagnostic strategies, preventive measures, and tailored management approaches for CHF in the Khorezm region.

References

World Health Organization. (2023). Cardiovascular diseases (CVDs). WHO.

Ponikowski, P., Voors, A. A., Anker, S. D., et al. (2021). 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 42(36), 3599-3726.

Savarese, G., & Lund, L. H. (2017). Global public health burden of heart failure. Cardiac Failure Review, 3(1), 7-11.

Yancy, C. W., Jessup, M., Bozkurt, B., et al. (2017). 2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure. Journal of the American College of Cardiology, 70(6), 776-803.

McDonagh, T. A., Metra, M., Adamo, M., et al. (2021). Heart failure management in Europe: current challenges and future solutions. European Heart Journal, 42(23), 2229-2241.

McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., … & Chioncel, O. (2021). 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 42(36), 3599–3726. https://doi.org/10.1093/eurheartj/ehab368

Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G. F., Coats, A. J. S., … & van der Meer, P. (2016). 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 37(27), 2129–2200. https://doi.org/10.1093/eurheartj/ehw128

Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey Jr, D. E., Colvin, M. M., … & Westlake, C. (2017). 2017 ACC/AHA/HFSA Focused update of the 2013 ACCF/AHA guideline for the management of heart failure. Circulation, 136(6), e137–e161. https://doi.org/10.1161/CIR.0000000000000509

Fuster, V., Harrington, R. A., Narula, J., & Eapen, Z. J. (Eds.). (2022). Hurst's the Heart, 15th Edition. New York, NY: McGraw-Hill Education.

Otto, C. M., & Prendergast, B. (2021). Echocardiography in heart failure management. New England Journal of Medicine, 385(2), 145–155. https://doi.org/10.1056/NEJMra2031571

Peacock, W. F., De Marco, T., Fonarow, G. C., Diercks, D., Wynne, J., & Apple, F. S. (2008). Cardiac troponin and outcome in acute heart failure. New England Journal of Medicine, 358(20), 2117–2126. https://doi.org/10.1056/NEJMoa0706824

Kellum, J. A., Lameire, N., & Aspelin, P. (2012). Kidney disease: Improving global outcomes (KDIGO) clinical practice guideline for acute kidney injury. Kidney International Supplements, 2(1), 1–138. https://doi.org/10.1038/kisup.2012.1