COGNITIVE IMPAIRMENTS IN CHILDREN FOLLOWING TRAUMATIC BRAIN INJURY: CLINICAL SPECTRUM, NEUROPSYCHOLOGICAL ASSESSMENT, AND REHABILITATION OUTCOMES

Authors

  • Abduxalimov Mashhurbek Baxromjon ugli, Xojimatova Malika Shuxratovna Department of Neurology, Andijan State Medical Institute, Andijan, Uzbekistan

Keywords:

traumatic brain injury, pediatric, cognitive impairment, neuropsychological assessment, rehabilitation, attention, executive function.

Abstract

Traumatic brain injury (TBI) is one of the leading causes of acquired cognitive disability in the pediatric population worldwide. Children who sustain mild, moderate, or severe TBI frequently demonstrate lasting deficits in attention, memory, executive function, processing speed, and academic achievement. The heterogeneity of injury severity and developmental stage at the time of injury complicates both diagnosis and treatment planning. This review aims to systematically characterize the spectrum of cognitive impairments observed after pediatric TBI, discuss validated neuropsychological assessment instruments, and summarize evidence-based rehabilitation strategies reported in recent literature. A narrative review was conducted of peer-reviewed publications indexed in PubMed, Scopus, and Google Scholar from 2005 to 2024. Studies involving children aged 0–17 years with diagnosed TBI and cognitive outcome data were included. Case reports and studies without control groups were excluded. Attention and working memory deficits are the most consistently reported sequelae across all TBI severity levels. Executive dysfunction, particularly in planning, cognitive flexibility, and inhibitory control, is prevalent in moderate-to-severe TBI. Age at injury is a critical moderator: injuries sustained before age five carry higher risk of pervasive cognitive delay due to disruption of ongoing brain maturation. Neuropsychological batteries such as NEPSY-II and the Cogstate Brief Battery demonstrate strong sensitivity for pediatric post-TBI assessment. Cognitive rehabilitation incorporating goal management training and computerized attention training shows moderate-to-large effect sizes.

References

Dewan MC, Rattani A, Gupta S, et al. Estimating the global incidence of traumatic brain injury. J Neurosurg. 2019;130(4):1080–1097. doi:10.3171/2017.10.JNS17352

Faul M, Coronado V. Epidemiology of traumatic brain injury. Handb Clin Neurol. 2015;127:3–13. doi:10.1016/B978-0-444-52892-6.00001-5

Anderson V, Catroppa C, Morse S, Haritou F, Rosenfeld JV. Functional plasticity or vulnerability after early brain injury? Pediatrics. 2005;116(6):1374–1382.

Anderson VA, Spencer-Smith M, Wood A. Do children really recover better? Neurobehavioural plasticity after early brain insult. Brain. 2011;134(Pt 8):2197–2221.

Babikian T, Asarnow R. Neurocognitive outcomes and recovery after pediatric TBI: meta-analytic review of the literature. Neuropsychology. 2009;23(3):283–296.

Gururaj G. Epidemiology of traumatic brain injuries: Indian scenario. Neurol Res. 2002;24(1):24–28.

Werner C, Engelhard K. Pathophysiology of traumatic brain injury. Br J Anaesth. 2007;99(1):4–9.

Bigler ED. Neuropsychology and clinical neuroscience of persistent post-concussive syndrome. J Int Neuropsychol Soc. 2008;14(1):1–22.

Wozniak JR, Krach L, Ward E, et al. Neurocognitive and neuroimaging correlates of pediatric traumatic brain injury. Arch Clin Neuropsychol. 2007;22(5):555–568.

Levin HS, Hanten G, Roberson G, et al. Prediction of cognitive sequelae based on abnormal computed tomography findings in children following mild traumatic brain injury. J Neurosurg Pediatr. 2008;1(6):461–470.

Giza CC, Hovda DA. The neurometabolic cascade of concussion. J Athl Train. 2001;36(3):228–235.

Zelazo PD, Carlson SM. Hot and cool executive function in childhood and adolescence: development and plasticity. Child Dev Perspect. 2012;6(4):354–360.

Scheibel RS, Newsome MR, Troyanskaya M, et al. Effects of severity of traumatic brain injury and brain reserve on cognitive-control related brain activation. J Neurotrauma. 2009;26(9):1447–1461.

Sinopoli KJ, Dennis M. Inhibitory control after traumatic brain injury in children. Int J Dev Neurosci. 2012;30(3):207–215.

Levin HS, Hanten G. Executive functions after traumatic brain injury in children. Pediatr Neurol. 2005;33(2):79–93.

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Published

2026-04-16

How to Cite

Abduxalimov Mashhurbek Baxromjon ugli, Xojimatova Malika Shuxratovna. (2026). COGNITIVE IMPAIRMENTS IN CHILDREN FOLLOWING TRAUMATIC BRAIN INJURY: CLINICAL SPECTRUM, NEUROPSYCHOLOGICAL ASSESSMENT, AND REHABILITATION OUTCOMES. Ethiopian International Journal of Multidisciplinary Research, 13(4), 1147–1153. Retrieved from https://www.eijmr.org/index.php/eijmr/article/view/6136