CONTEMPORARY UNDERSTANDING OF THE CLINICAL FEATURES OF RHEUMATOID ARTHRITIS AND METHODS OF ITS THERAPY
Keywords:
Rheumatoid arthritis, clinical features, immunopathogenesis, modern methods of therapy, medial unicondylar knee arthroplasty.Abstract
In recent years, rheumatoid arthritis has become a global problem, affecting 0.5-2% of the population over the age of 50 (up to 6% among women).The annual increase in new cases is 0.02%. The disease is also considered, a social issue, leading to disability among patients in young and middle-aged groups. The disease is based on joint structure disorders ankylosis, deformities, and contractures. The degree of their development is closely related to early initiation of treatment. This review article presents modern perspectives on the clinical features and treatment of rheumatoid arthritis.
References
Abdurakhmanova N., Akhmedov Kh. Effect of pro-inflammatory cytokine-Interleukin-6 on the course of ankylosing spondylitis in patients after COVID-19//Annals of the Rheumatic Diseases. - 2022. - S. 1533-1533.
Abdurakhmanova, N. M., and S. S. Rakhimov. "Genetic Aspects of Methotrexate Resistance Treatment in Patients with Rheumatoid Arthritis." (2023).
Nasonov, Evgeny Lvovich, Lila A. M. "Baricitinib: New Opportunities for Pharmacotherapy of Rheumatoid Arthritis and Other Immune-Inflammatory Rheumatic Diseases." Scientific and Practical Rheumatology. 2020, No. 3.
Abdelhafiz D, Baker T, Glascow DA, Abdelhafiz A. "Biomarkers for the Diagnosis and Treatment of Rheumatoid Arthritis - A Systematic Review." Postgrad Med. 2023;135(3):214-223. doi:10.1080/00325481.2022.2052626
Abdurakhmanova N. M., Jabbarov O. O., Tursunova L. D. "Influence of Mdr1 Gene Polymorphism on the Course of Rheumatoid Arthritis." NATURALISTA CAMPANO. 2024, Vol. 28, No. 1, pp. 3010-3015.
Abdurakhmanova, Nargiza, Khalmurad Akhmedov. "Influence of C3435T MDR1 Gene Polymorphism on Methotrexate Resistance in Patients with Rheumatoid Arthritis." (2019).
Cao J, Wang W, Feng W, Xu H, Wang D, Zhou Z. "Staged Replacement of Both Hips and Both Knees in Patients with Rheumatoid Arthritis." BMC Musculoskelet Disord. 2023;24(1):231. Published March 28, 2023. doi:10.1186/s12891-023-06282-4
Fan Y, Wang Z, Weng XS, et al. "Cemented Total-Knee Arthroplasty in Rheumatoid Arthritis Patients Aged Under 60 Years." Chin Med J (Engl). 2019;132(22):2760-2761. doi:10.1097/CM9.0000000000000502
Frazzei G, Musters A, de Vries N, Tas SW, van Vollenhoven RF. "Prevention of Rheumatoid Arthritis: A Systematic Literature Review of Preventive Strategies in At-Risk Individuals." Autoimmun Rev. 2023;22(1):103217. doi:10.1016/j.autrev.2022.103217
Fujiwara T, Fujimura K, Hamai S, Kamura S, Nakashima Y, Miyahara H. "Mid-Term Clinical Outcome of Constrained Condylar Knee Prosthesis for Patients with Rheumatoid Arthritis." Mod Rheumatol. 2019;29(4):596-601. doi:10.1080/14397595.2018.1486954
Gessl I, Hana CA, Deimel T, et al. "Tenderness and Radiographic Progression in Rheumatoid Arthritis and Psoriatic Arthritis." Ann Rheum Dis. 2023;82(3):344-350. doi:10.1136/ard-2022-222787
Huang J, Fu X, Chen X, Li Z, Huang Y, Liang C. "Promising Therapeutic Targets for Treatment of Rheumatoid Arthritis." Front Immunol. 2021;12:686155. Published July 9, 2021. doi:10.3389/fimmu.2021.6861554
Khalmetova, F. I., X. S. Akhmedov, and G. A. Alibekova. "Features of the Course of the Joint Syndrome in Various Forms of Reactive Arthritis." Galaxy International Interdisciplinary Research Journal 11.4 (2023): 832-837.






Azerbaijan
Türkiye
Uzbekistan
Kazakhstan
Turkmenistan
Kyrgyzstan
Republic of Korea
Japan
India
United States of America
Kosovo