INTEGRATION OF MORPHOMETRIC AND MORPHOLOGICAL METHODS IN THE COMPREHENSIVE ASSESSMENT OF KIDNEY TRANSPLANT FUNCTION

Muminov Javohir Asliddinovich

Authors

Muminov Javohir Asliddinovich Independent Researcher, Abu Ali ibn Sino Bukhara State Medical Institute

Keywords:

kidney transplantation, ultrasound morphometry, morphology, Banff classification, resistive index, correlation analysis.

Abstract

Objective: To evaluate the informativeness of morphometric, ultrasound, and morphological methods for diagnosing the functional status of kidney grafts in the early postoperative period. The study included 72 recipients divided into two groups according to sensitization level (MFK-1, n = 41; MFK-2, n = 31). Serial ultrasound measurements of renal size, parenchymal thickness, and resistive index (RI) were performed, together with morphometric analysis of biopsy specimens according to Banff (2017) and assessment of correlations between functional, hemodynamic, and histological parameters. A significant correlation was found between elevated RI and the severity of interstitial-tubular changes (r = 0.68; p = 0.01). The combination of instrumental and morphological methods increases the diagnostic accuracy of early graft function assessment.

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