COVID-19 AND THROMBOSIS: HEMOSTATIC DISORDERS IN THE CARDIOVASCULAR SYSTEM
Keywords:
COVID-19, SARS-CoV-2, thrombosis, hemostasis, coagulopathy, endothelium, platelet activation, cardiovascular system, venous thromboembolism, pulmonary embolism, myocardial infarction, stroke, microthrombosis, inflammation, D-dimer.Abstract
COVID-19 is now understood not only as a respiratory infection but also as a systemic vascular and thromboinflammatory disease. Since the early phases of the pandemic, clinical and pathological studies have shown that SARS-CoV-2 infection can disturb hemostatic balance, activate coagulation pathways, injure the endothelium, alter platelet function, impair fibrinolysis, and trigger both venous and arterial thrombosis.
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